Visual and Auditory Complications of Chronic Myeloid Leukemia: A Case Report
O. A. Ejele
Haematology Department, University of Port Harcourt Teaching Hospital (UPTH), Nigeria.
H. E. Omunakwe *
Haematology Department, University of Port Harcourt Teaching Hospital (UPTH), Nigeria.
C. Iyalla
Haematology Department, University of Port Harcourt Teaching Hospital (UPTH), Nigeria.
O. B. da Lilly-Tariah
ENT Department, UPTH, Nigeria.
C.N. Pedro-Egbe
Ophthalmology Department UPTH, Nigeria.
*Author to whom correspondence should be addressed.
Abstract
Hearing loss and visual impairment are not common presentations of Chronic Myeloid Leukemia (CML). We report such a case who presented in the chronic phase with profound hearing loss, visual impairment, progressively enlarging spleen, anaemia, and weight loss.
Laboratory evaluation showed Packed Cell Volume – 10%, Total White Cell Count – 1,343 x 109/ L, Platelets – 589 x 109/ L. Blood chemistry showed Uric Acid level of 530mmol/L. Karyotyping showed the Philadelphia chromosome.
Chemotherapy was instituted and she improved remarkably with minimal improvement in perception of sound.
Keywords: Chronic myeloid leukaemia, visual impairment, hearing loss.