Frequency Distribution of Hemoglobin Variants among Teenagers
A. A. Adeyemi *
Department of Hematology, Babcock University, Ilisan-Remo, Ogun-State, Nigeria.
A. O. Ladipo
Department of Chemical Pathology, Babcock University Teaching Hospital, Ilisan-Remo, Ogun-State, Nigeria.
O. A. Omolade
Department of Community Medicine and Primary Care, Olabisi Onabanjo University, Sagamu, Ogun-State, Nigeria.
D. D. Ogbaro
Department of Hematology, Babcock University, Ilisan-Remo, Ogun-State, Nigeria.
*Author to whom correspondence should be addressed.
Abstract
Aim: The intent of this study is to report the distribution of hemoglobin variants among teenagers in South -West Nigeria.
Study Design: Cross sectional study.
Place/Duration: Babcock University, Ilisan-Remo, Ogun State, South-West Nigeria between September 2013 and March 2015.
Methods: Hemoglobin (Hb) variants were determined in two thousand, four hundred and six teenagers using the alkaline electrophoresis method.
Results: The distribution of Hemoglobin electrophoresis is as follows; HbAA 1821 (75.7%), HbAS 498 (20.7%), HbAC 47 (2.0%), HbCC 01 (0.0%), HbSC 12 (0.5%), HbSS 27 (1.1%).
Conclusion: The incidence of hemoglobinopathies is reduced among the teenagers in South- West Nigeria.
Keywords: Incidence, hemoglobinopathies, sickle cell trait, Nigeria, sickle cell disease, teenagers