Microalbuminuria in Patients with Recent Ischaemic Cerebrovascular Stroke: A Cross Sectional Study
Shivnarayan Pattanaik
SCB Medical College, University of Utkal, Cuttack, Odisha-753001, India.
Purna Chandra Dash *
SCB Medical College, University of Utkal, Cuttack, Odisha-753001, India.
*Author to whom correspondence should be addressed.
Abstract
Objectives: Microalbuminuria is an integrated marker of both kidney disease and endothelial dysfunction may be associated with global vascular risk. The purpose of the study was to assess the association of microalbuminuria with risk of nondiabetic nonhypertensive ischaemic stroke.
Materials and Methods: 60 cases of recent ischaemic strokes clinically diagnosed by WHO criteria and confirmed by CT scan of brain admitted to SCB Medical College and Hospital were studied. Diabetes mellitus, family history of DM, hypertension, nephropathy, atrial fibrillation, chronic liver disease, systemic infection, neoplasm, recent myocardial infection, females during menstruation and pregnancy were excluded from the study.
Results: Total number of 60 patients were studied, out of which male (35)58.3% and female (25)41.6%. Most of patients were in age group between 50-70 years. Mean age of presentation with microalbuminuria was 60.71 years. Microalbuminuria present in (29)48.33% of cases as compared to (3) 10% of controls. Severity of stroke was assessed by Scandinavian Stroke scale, was lower in presence of microalbuminuria (16±9.04) than without microalbumunuria (22±12.5).
Conclusion: The above study shows that there is increased incidence of microalbuminuria in recent ischaemic stroke and the microalbuminuria increases with severity of stroke.
Keywords: Endothelial dysfunction, Microalbuminuria (MA), ischaemic stroke, scandinavian stroke scale.