Assessing the Role of Comorbidities Associated with Tuberculosis in Ouagadougou, Burkina Faso
Maïga Soumaïla *
Pneumology Department, Yalgado Ouédraogo University Hospital, Ouagadougou, Burkina Faso.
Ouédraogo Gafourou Arsène
Infectious Diseases Department, Yalgado Ouédraogo University Hospital, Ouagadougou, Burkina Faso.
Ali Moussa Mahaman Laouali
Pneumology Department, Yalgado Ouédraogo University Hospital, Ouagadougou, Burkina Faso.
Ouattara Aïsseta Yasmine
Pneumology Department, Yalgado Ouédraogo University Hospital, Ouagadougou, Burkina Faso.
Zonon Hamadé
Infectious Diseases Department, Yalgado Ouédraogo University Hospital, Ouagadougou, Burkina Faso.
Bonsa Edmond
Pneumology Department, Yalgado Ouédraogo University Hospital, Ouagadougou, Burkina Faso.
Ouedraogo Abdoul Risgou
Pneumology Department, Tengandogo University Hospital, Ouagadougou, Burkina Faso and Joseph Ki ZERBO University, Ouagadougou, Burkina Faso.
Boncoungou Kadiatou
Pneumology Department, Yalgado Ouédraogo University Hospital, Ouagadougou, Burkina Faso and Joseph Ki ZERBO University, Ouagadougou, Burkina Faso.
Badoum Gisèle
Pneumology Department, Yalgado Ouédraogo University Hospital, Ouagadougou, Burkina Faso and Joseph Ki ZERBO University, Ouagadougou, Burkina Faso.
Martial Ouédraogo
Pneumology Department, Yalgado Ouédraogo University Hospital, Ouagadougou, Burkina Faso and Joseph Ki ZERBO University, Ouagadougou, Burkina Faso.
*Author to whom correspondence should be addressed.
Abstract
Introduction: Tuberculosis remains a public health problem. The objective of this study was to investigate the comorbidities associated with this disease in the city of Ouagadougou.
Methodology: This was a retrospective cohort study with a descriptive and analytical purpose, conducted on drug-susceptible tuberculosis patients followed in four tuberculosis diagnosis and treatment centers.
Results: A total of 408 cases of drug-susceptible tuberculosis of all forms were included in our study. The mean age of the patients was 39.41 + -15.84 years, with a range of 15 to 80 years, and more than half were from the informal sector (61.76%). There were 86.27% new cases and 13.73% previously treated patients. Smoking and alcoholism were found in the population studied. A prevalence of 68.62% of patients had at least one comorbidity, the most common of which were malnutrition, hypertension and TB/HIV coinfection. Treatment failure was more common among patients without comorbidities (8.57% vs. 12.5%, p=0.112), and there were also more lost to follow-up (5.17% vs. 0%, p=0.01) in this group.
Conclusion: Comorbidities are factors that influence the effectiveness of tuberculosis treatment. In our study, 68.62% of patients had at least one comorbidity. The most common comorbidities were malnutrition, high blood pressure, and TB/HIV co-infection.
Keywords: Tuberculosis, comorbidities, Ouagadougou, Burkina Faso