Single Bone Metastasis of a Squamous Cell Carcinoma of the Cervix: In the Clavicle

Imane Chahbounia *

Medical Oncology Department, Mohamed V Military Instruction Hospital, Rabat, Morocco.

Abdelkarim Poudiougou

Medical Oncology Department, Mohamed V Military Instruction Hospital, Rabat, Morocco and Medical Oncology Department, National Institute of Oncology, Rabat, Morocco.

Sofia El Omri

Medical Oncology Department, Mohamed V Military Instruction Hospital, Rabat, Morocco and Medical Oncology Department, National Institute of Oncology, Rabat, Morocco.

Imane Sella

Medical Oncology Department, Mohamed V Military Instruction Hospital, Rabat, Morocco and Medical Oncology Department, National Institute of Oncology, Rabat, Morocco.

Abdelkarim Antari

Medical Oncology Department, Mohamed V Military Instruction Hospital, Rabat, Morocco and Medical Oncology Department, National Institute of Oncology, Rabat, Morocco.

Faman Sano

Medical Oncology Department, Mohamed V Military Instruction Hospital, Rabat, Morocco and Medical Oncology Department, National Institute of Oncology, Rabat, Morocco.

Imad Taleb

Medical Oncology Department, Mohamed V Military Instruction Hospital, Rabat, Morocco and Medical Oncology Department, National Institute of Oncology, Rabat, Morocco.

Hamadoun Traoré

Medical Oncology Department, Mohamed V Military Instruction Hospital, Rabat, Morocco and Medical Oncology Department, National Institute of Oncology, Rabat, Morocco.

Mohammed Amine Saad

Medical Oncology Department, Mohamed V Military Instruction Hospital, Rabat, Morocco and Medical Oncology Department, National Institute of Oncology, Rabat, Morocco.

Khaoula Alaoui Slimani

Medical Oncology Department, Mohamed V Military Instruction Hospital, Rabat, Morocco and Medical Oncology Department, National Institute of Oncology, Rabat, Morocco.

Lamiaa Aalaoui

Medical Oncology Department, Mohamed V Military Instruction Hospital, Rabat, Morocco and Medical Oncology Department, National Institute of Oncology, Rabat, Morocco.

Saida Lamine

Medical Oncology Department, Mohamed V Military Instruction Hospital, Rabat, Morocco and Medical Oncology Department, National Institute of Oncology, Rabat, Morocco.

Adil Debbagh

Medical Oncology Department, Mohamed V Military Instruction Hospital, Rabat, Morocco and Medical Oncology Department, National Institute of Oncology, Rabat, Morocco.

Mohammed Reda Khmamouche

Medical Oncology Department, Mohamed V Military Instruction Hospital, Rabat, Morocco and Medical Oncology Department, National Institute of Oncology, Rabat, Morocco.

Choukri Elm’hadi

Medical Oncology Department, Mohamed V Military Instruction Hospital, Rabat, Morocco and Medical Oncology Department, National Institute of Oncology, Rabat, Morocco.

Tarik Mahfoud

Medical Oncology Department, Mohamed V Military Instruction Hospital, Rabat, Morocco and Medical Oncology Department, National Institute of Oncology, Rabat, Morocco.

Mohammed Anouar Mokhlis

Medical Oncology Department, Mohamed V Military Instruction Hospital, Rabat, Morocco and Medical Oncology Department, National Institute of Oncology, Rabat, Morocco.

Yassir Sbitti

Medical Oncology Department, Mohamed V Military Instruction Hospital, Rabat, Morocco and Medical Oncology Department, National Institute of Oncology, Rabat, Morocco.

Mohammed Ichou

Medical Oncology Department, Mohamed V Military Instruction Hospital, Rabat, Morocco and Medical Oncology Department, National Institute of Oncology, Rabat, Morocco.

Hassan Errihani

Medical Oncology Department, Mohamed V Military Instruction Hospital, Rabat, Morocco and Medical Oncology Department, National Institute of Oncology, Rabat, Morocco.

Rachid Tanz

Medical Oncology Department, Mohamed V Military Instruction Hospital, Rabat, Morocco and Medical Oncology Department, National Institute of Oncology, Rabat, Morocco.

*Author to whom correspondence should be addressed.


Abstract

Cervical cancer occurs around the age of 40-45, and can be localized or metastatic.

Metastatic sites vary: lymph nodes, lungs and other sites. Bone metastases are uncommon, and require histological study to confirm their secondary nature, especially in the case of unusual localizations. Case report: we report the case of a young patient followed since 2022 for a moderately differentiated, infiltrating and keratinizing squamous cell carcinoma of the uterine cervix, classified IIb, treated with concomitant radio-chemotherapy. In early 2024, a surveillance thoraco-abdomino-pelvic CT scan showed a mixed lesion of the sternal end of the left clavicle. A PET-FDG scan showed an intense, heterogeneous, hypermetabolic condensing lesion. A biopsy confirmed the diagnosis: bone localization of a moderately differentiated squamous cell carcinoma. The patient was treated with chemotherapy, followed by surgery and local radiotherapy. Conclusion: a clavicular metastasis of a cervical cancer represents a rare entity, especially in the presence of a single secondary lesion, with no other metastases elsewhere. 

Keywords: Clavicle, bone metastasis, single lesion, cervical cancer


How to Cite

Chahbounia, Imane, Abdelkarim Poudiougou, Sofia El Omri, Imane Sella, Abdelkarim Antari, Faman Sano, Imad Taleb, et al. 2025. “Single Bone Metastasis of a Squamous Cell Carcinoma of the Cervix: In the Clavicle”. Journal of Advances in Medicine and Medical Research 37 (6):321-26. https://doi.org/10.9734/jammr/2025/v37i65875.

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