Efficacy of Tooth Bleaching with 35% and 6% Hydrogen Peroxide in Primary Dentition: Study Protocol for a Randomized Controlled Clinical Trial
Camilla Vieira Esteves
School of Dentistry, Universidade de São Paulo, São Paulo, Brazil.
Ana Paula Taboada Sobral
Postgraduation Programme in Health and Environment, Universidade Metropolitana de Santos, Santos, Brazil and School of Dentistry, Universidade Metropolitana de Santos, Santos, Brazil.
Marcela Leticia Leal Gonçalves
Postgraduation Programme in Health and Environment, Universidade Metropolitana de Santos, Santos, Brazil and School of Dentistry, Universidade Metropolitana de Santos, Santos, Brazil.
Thais Gimenez
School of Dentistry, Universidade de São Paulo, São Paulo, Brazil.
Juliana Maria Altavista Sagretti Gallo
Postgraduation Program in Veterinary Medicine in the Coastal Environment, Universidade Metropolitana de Santos, Santos, Brazil.
Solange Kobayashi-Velasco
School of Dentistry, Universidade de São Paulo, São Paulo, Brazil.
Aloísio de Melo Farias Neto
School of Dentistry, Universidade de Santo Amaro, São Paulo, Brazil.
Amanda Rafaelly Honório Mandetta
Postgraduation Programme in Biophotonics Applied to Health Sciences, Universidade Nove de Julho, São Paulo, Brazil.
Olga Maria Altavista
School of Dentistry, Universidade Nove de Julho, São Paulo, Brazil.
Marcelo Mendes Pinto
School of Dentistry, Universidade Nove de Julho, São Paulo, Brazil.
Anna Carolina Ratto Tempestini Horliana
Postgraduation Programme in Biophotonics Applied to Health Sciences, Universidade Nove de Julho, São Paulo, Brazil.
Lara Jansiski Motta
Postgraduation Programme in Biophotonics Applied to Health Sciences, Universidade Nove de Julho, São Paulo, Brazil.
Sandra Kalil Bussadori *
School of Dentistry, Universidade Metropolitana de Santos, Santos, Brazil and Postgraduation Programme in Biophotonics Applied to Health Sciences, Universidade Nove de Julho, São Paulo, Brazil.
*Author to whom correspondence should be addressed.
Abstract
Background: The aesthetics of dental elements generates significant psychological and social impacts, both in primary and permanent dentition. One of the most employed techniques to visually improve the appearance of teeth is bleaching. In in-office whitening, the technique used consists of applying whitening gel to dental surfaces in concentrations ranging from 25% to 50% of hydrogen peroxide. However, recent studies showed that low and medium concentration bleaching agents based on hydrogen peroxide have been effective and present a lower risk of sensitivity to the patient.
Aims: To carry out a controlled and randomized clinical trial to compare the effectiveness of dental bleaching in primary teeth with hydrogen peroxide at concentrations of 35% and 6%.
Methods: In this study, 38 patients aged 3 to 6 years-old will be selected and allocated in 2 groups (G1 - Hydrogen Peroxide 35%, n=19 and G2- Hydrogen Peroxide 6%, n=19). Bleaching will be carried out in up to three sessions, with an interval of 7 days between each session. Evaluation of color and tooth sensitivity will be carried out 48 hours after each bleaching session. The color assessment will be measured with the aid of a digital spectrometer while the tooth sensitivity will be assessed by using the Pain Level Scale (Wong-Baker Faces®).
Discussion: It is expected that there will be no significant difference between the groups in terms of color variation and that the low concentration bleaching group will have the lowest sensitivity index.
Keywords: Tooth bleaching, tooth bleaching agents, hydrogen peroxide, primary dentition, tooth deciduous