Efficacy of Standardized Rhodiola rosea Dry Extract in Managing Stress Levels among Healthcare Professionals

Jeane Castro Fonseca *

Basic and Health Sciences Laboratory (LaCiBS), Master's Program in Health Sciences, Doctoral Program in Biodiversity and Biotechnology – Bionorte, Federal University of Tocantins, Brazil.

Ellen Lima Pessoa

Basic and Health Sciences Laboratory (LaCiBS), Master's Program in Health Sciences, Doctoral Program in Biodiversity and Biotechnology – Bionorte, Federal University of Tocantins, Brazil.

Tayslane Dias Castro

Basic and Health Sciences Laboratory (LaCiBS), Master's Program in Health Sciences, Doctoral Program in Biodiversity and Biotechnology – Bionorte, Federal University of Tocantins, Brazil.

Samila Matias Santos

Basic and Health Sciences Laboratory (LaCiBS), Master's Program in Health Sciences, Doctoral Program in Biodiversity and Biotechnology – Bionorte, Federal University of Tocantins, Brazil.

Fernanda Pereira dos Santos

Basic and Health Sciences Laboratory (LaCiBS), Master's Program in Health Sciences, Doctoral Program in Biodiversity and Biotechnology – Bionorte, Federal University of Tocantins, Brazil.

Larissa Caroline da Silva Marinho

Basic and Health Sciences Laboratory (LaCiBS), Master's Program in Health Sciences, Doctoral Program in Biodiversity and Biotechnology – Bionorte, Federal University of Tocantins, Brazil.

Guilherme Nobre Lima do Nascimento

Basic and Health Sciences Laboratory (LaCiBS), Master's Program in Health Sciences, Doctoral Program in Biodiversity and Biotechnology – Bionorte, Federal University of Tocantins, Brazil.

*Author to whom correspondence should be addressed.


Abstract

Aims: The objective was to evaluate the effect of using a standardized dry extract of Rhodiola rosea in stress management.

Methodology: The study was a randomized, placebo-controlled clinical trial. It was conducted at a hospital in Palmas, Tocantins, Brazil. It was conducted with 25 healthcare professionals, divided into control and placebo groups, where a dose of 210mg of Rhodiola rosea was used for 15 days in the control group. A perceived stress scale was applied, anthropometric measurements were taken, and laboratory samples were collected.

Results: The sample, predominantly female (88%), was composed of professionals in various healthcare roles, most working in a 12-hour shift system. The findings indicated that a significant portion of participants (52%) felt dissatisfied with their body weight, with 36% categorized as overweight or obese based on BMI. Additionally, 48% had waist circumference values indicating an increased risk for chronic diseases. The stress level assessment using the Perceived Stress Scale showed no statistical difference between those using Rhodiola rosea extract and the placebo, despite previous studies suggesting Rhodiola's efficacy in stress reduction. The lack of significant results in this study contrasts with other research that demonstrated the effectiveness of Rhodiola rosea in improving stress-related symptoms.

Conclusion: The results showed no significant difference between the use of the herbal medicine and the placebo in improving stress.

Keywords: Rhodiola rosea, herbal medicine, stress


How to Cite

Fonseca, Jeane Castro, Ellen Lima Pessoa, Tayslane Dias Castro, Samila Matias Santos, Fernanda Pereira dos Santos, Larissa Caroline da Silva Marinho, and Guilherme Nobre Lima do Nascimento. 2025. “Efficacy of Standardized Rhodiola Rosea Dry Extract in Managing Stress Levels Among Healthcare Professionals”. Journal of Advances in Medicine and Medical Research 37 (2):9-18. https://doi.org/10.9734/jammr/2025/v37i25716.

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