Femur Fracture Management in a Newborn with Osteogenesis Imperfecta: A Case Report

Henrique Costa Sardinha

Medical School at Evangelical University of Goiás - UniEVANGÉLICA, Anápolis, GO, Brazil.

Leonardo Pinheiro Rezende *

Medical School at Evangelical University of Goiás - UniEVANGÉLICA, Anápolis, GO, Brazil.

Fábio Felippe da Silva

State Hospital of Anápolis Dr. Henrique Santillo (HEANA), Brazil.

Ananda Camille Silva Oliveira

Medical School at Evangelical University of Goiás - UniEVANGÉLICA, Anápolis, GO, Brazil.

Mariana Bessa Marinho

Medical School at Evangelical University of Goiás - UniEVANGÉLICA, Anápolis, GO, Brazil.

Julie Paiva Souza

Medical School at Evangelical University of Goiás - UniEVANGÉLICA, Anápolis, GO, Brazil.

Lana Gabriely Jarina de Almeida

Medical School at Evangelical University of Goiás - UniEVANGÉLICA, Anápolis, GO, Brazil.

Laura Marques Santos

Medical School at Evangelical University of Goiás - UniEVANGÉLICA, Anápolis, GO, Brazil.

Humberto de Sousa Fontoura

Medical School at Evangelical University of Goiás - UniEVANGÉLICA, Anápolis, GO, Brazil.

*Author to whom correspondence should be addressed.


Abstract

Aims: This article aims to report a case of osteogenesis imperfecta from an orthopedic perspective, highlighting a study on the orthopedic management of a femur fracture.

Presentation of Case: A five-day-old Brazilian male neonate of South American ethnicity was diagnosed with type III osteogenesis imperfecta. Imaging tests identified common clinical manifestations of this disease. Bryant's traction was applied to immobilize the right femur, Pavlick's brace was used, and pamidronate disodium was prescribed. One month after birth, the patient was discharged from the Intensive Care Unit with excellent outcomes.

Discussion: Osteogenesis imperfecta (OI) is a rare genetic disorder characterized by bone fragility and low bone mineral density, resulting in recurrent fractures. OI is classified into five types based on severity. Clinical manifestations include skeletal weakening, blue sclera, and deafness. Diagnosis during intrauterine life remains challenging, while fractures during pregnancy are atypical. Management necessitates a multidisciplinary approach, incorporating orthoses, physiotherapy, and pharmacological interventions, which improves bone density but poses risks with prolonged use. Fracture treatment emphasizes minimal immobilization, physiotherapy, and tailored neonatal interventions such as Bryant traction. Patient and caregiver education is integral to optimizing outcomes in OI care.

Conclusion: This is a case report of a newborn with osteogenesis imperfecta (OI) who received treatment for a femur fracture. OI is a rare disease that can have a significant impact on affected patients. Therefore, it is essential to document treatment options and outcomes to contribute to the global database on this rare pathology.

Keywords: Osteogenesis imperfecta, orthopedics, femur fracture, lacunal skull


How to Cite

Sardinha, Henrique Costa, Leonardo Pinheiro Rezende, Fábio Felippe da Silva, Ananda Camille Silva Oliveira, Mariana Bessa Marinho, Julie Paiva Souza, Lana Gabriely Jarina de Almeida, Laura Marques Santos, and Humberto de Sousa Fontoura. 2025. “Femur Fracture Management in a Newborn With Osteogenesis Imperfecta: A Case Report”. Journal of Advances in Medicine and Medical Research 37 (1):202-8. https://doi.org/10.9734/jammr/2025/v37i15708.

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