Efficacy and Safety of Photobiomodulation on Non-infected Pressure Ulcer in Adults: A Study Protocol of Randomized Clinical Trials
Adriana da Silva Magalhães
Postgraduate Program in Biophotonics-Medicine, Universidade Nove de Julho (UNINOVE), São Paulo, Brazil
Lara Jansiski Motta
Postgraduate Program in Biophotonics-Medicine, Universidade Nove de Julho (UNINOVE), São Paulo, Brazil
Isabel Veloso Alves Pereira
Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
Sandra Kalil Bussadori
Postgraduate Program in Biophotonics-Medicine, Universidade Nove de Julho (UNINOVE), São Paulo, Brazil and Postgraduate Program in Reabilitation Sciences, Universidade Nove de Julho (UNINOVE), São Paulo, Brazil.
Cinthya Cosme Gutierrez Duran
Postgraduate Program in Biophotonics-Medicine, Universidade Nove de Julho (UNINOVE), São Paulo, Brazil
Kristianne Porta Santos Fernandes
Postgraduate Program in Biophotonics-Medicine, Universidade Nove de Julho (UNINOVE), São Paulo, Brazil
Raquel Agnelli Mesquita-Ferrari
Postgraduate Program in Biophotonics-Medicine, Universidade Nove de Julho (UNINOVE), São Paulo, Brazil and Postgraduate Program in Reabilitation Sciences, Universidade Nove de Julho (UNINOVE), São Paulo, Brazil.
Anna Carolina Ratto Tempestini Horliana *
Postgraduate Program in Biophotonics-Medicine, Universidade Nove de Julho (UNINOVE), São Paulo, Brazil
*Author to whom correspondence should be addressed.
Abstract
Pressure injuries (PIs) are a significant public health issue, causing harm and compromising the safety of hospitalized patients. Some studies suggest that photobiomodulation may promote anti-inflammatory effects and wound revascularization, accelerating the healing process in skin wounds. However, the quality of evidence remains limited. Objective: To evaluate the effectiveness and safety of photobiomodulation as a treatment for non-infected PIs in adults. Methods: It followed the methodological guidelines of the Cochrane Handbook for Systematic Reviews of Interventions and the PRISMA Statement. A systematic search for randomized controlled trials (RCTs) will be conducted in databases from their inception to December 2024 without language restrictions. The databases included MEDLINE, EMBASE, CENTRAL, LILACS, BBO, ICTRP, ClinicalTrials.gov, WHO, and OpenGrey.
PROSPERO Registration Number: CRD42020200637.
Keywords: Systematic review, pressure injury, photobiomodulation, wound healing