The Clinical and Histopathological Characteristics of Breast Lesions in Western Sudan
Tumadir Mohammed Adam
Department of Histopathology and Cytology,Faculty of Medical Laboratory Sciences, University of Kordofan, El-Obeid, Sudan.
Ahmed Abdulla Agabeldour
Department of Pathology, Faculty of Medicine, University of Kordofan, Kordofan Histopathology Center, Sudan.
Hasabsidu Adam Dafea
Department of General Surgery, General, EL-Obeid Teaching Hospital, El-Obeid, Sudan.
Esraa Daffalla Mohamed Ahmed
Department of Surgery, Faculty of Medicine, University of Kordofan, El-Obeid, Sudan.
Mirghani Kamal Eldin Mirghani Ahmed
Registrar Obstetrics and Gynecology, Sudan Medical Specialization Board, Sudan.
Tasneem Alfaki Mohamedelnour Monwer
Department of Clinical Pharmacy at Pediatrics Department, EL-Obeid Teaching Hospital, El-Obeid, Sudan.
Maysa Khowgali AbdAlla Babker
Department of microbiology, Faculty of Medical Laboratory Sciences, University of Kordofan, El-Obeid, Sudan.
Amal Khalil Yousif Mohammed
Department of Medicine, Faculty of Medicine, University of Kordofan, El-Obeid, Sudan and Aldaman International Hospital, El-Obeid, Sudan.
Eldisugi Hassan Mohammed Humida
Department of Medicine, Faculty of Medicine, University of Kordofan, El-Obeid, Sudan, EL-Obeid International Hospital – Director of Cardiac Catheterization Laparotomy, Sudan and EL-Obeid Teaching Hospital, El-Obeid, Sudan.
Mustafa Elnour Hussein Bahar
University of Khartoum, Faculty of Medicine, Suba university hospital, Khartoum, Sudan.
Hikmat Siddig Elzain Elnour
Department of Microbiology, Faculty of Medical Laboratory Sciences, University of Kordofan, El-Obeid, Sudan.
Tomadir Elfaki Mohamedelnour Monawer
Department of General Surgery, EL-Obeid Teaching Hospital, El-Obeid, Sudan.
Gesmelseid Abdelader Gesmelseid Saror
University of Kordofan, Faculty of Medicine, Registrar Obstetrics and Gynecology, Sudan Medical Specialization Board, EL-Obeid Teaching hospital, El-Obeid, Sudan.
Najla Adam Elsharif Salem
Medical Research Consultancy Center, El-Obeid, NK, Sudan.
Khalid Nasralla Habeeballa Hashim
Department of Obstetrics and Gynecology, Faculty of Medicine, Qassim University, Saudi Arabia.
Hussain Gadelkarim Ahmed *
Medical Research Consultancy Center, El-Obeid, NK, Sudan and Department of Histopathology and Cytology, FMLS, University of Khartoum, Khartoum, Sudan.
*Author to whom correspondence should be addressed.
Abstract
Background: Presenting advanced breast cancer in Sudan is a significant challenge. Consequently, the objective of this investigation was to evaluate the breast lesion pattern in Western Sudan.
Methodology: This study was a retrospective descriptive analysis carried out in two major entities that offer histopathology services in the northern region of Kordofan State. The study encompassed a total of 190 patients, with 110 of them having malignant lesions and 79 having benign breast lesions.
Results: Among the 110 cases of breast cancer, 59% were classified as invasive ductal carcinoma (DC), 12.7% as infiltrating DC, and 9% as invasive lobular carcinoma (LC). We identified 37.9% of the 79 non-cancerous growths as fibroadenoma, 25.3% as fibrocystic changes, and 6.3% as Phyllodes tumors.
Conclusion: In Sudan, the advanced presentation of breast cancer is common. When a patient presents with a lump, the likelihood of a malignant diagnosis is higher. Breast cancer is a significant concern for younger Sudanese women, particularly those under the age of 45 years.
Keywords: Breast cancer, fibroadenoma, fibrocystic change, ductal carcinoma, lobular carcinoma