Mandibular Mobilization in Individuals with Anterior Disc Displacement with Magnetic Resonance Imaging Assessment: A Study Protocol
Cintia Moraes Gutierrez
Universidade Nove de Julho, São Paulo, Brasil.
Taisi Antunes Da Cunha
Universidade Nove de Julho, São Paulo, Brasil.
Fabiana Alves da Silva Xavier
Universidade Nove de Julho, São Paulo, Brasil.
Fernanda Cardoso Nakamoto
Universidade Nove de Julho, São Paulo, Brasil.
Margarete Nobilo Leonardis
Universidade Nove de Julho, São Paulo, Brasil.
Cid André Fidelis De Paula Gomes
Universidade Nove de Julho, São Paulo, Brasil.
Fabiano Politti
Universidade Nove de Julho, São Paulo, Brasil.
Daniela Aparecida Biasotto-Gonzalez *
Universidade Nove de Julho, São Paulo, Brasil.
*Author to whom correspondence should be addressed.
Abstract
Objective: To assess the influence of mandibular mobilization on the positioning of the articular disc using magnetic resonance imaging (MRI) in participants with anterior disc displacement, with and without reduction, immediately after treatement, and at 3 and 6 months post-treatment.
Study Design: Controlled, randomized clinical trial with blinded evaluators and participants.
Methodology: Individuals aged 18-45 years with an MRI-confirmed diagnosis of anterior disc displacement.
Intervention: Two groups: GA (intervention) and GB (placebo), each receiving 12 treatment sessions.
Main Outcome Measures: Disc positioning assessed by MRI before and after the final session, as well as at 3- and 6-month follow-ups.
Analysis: Statistical analysis will be conducted using linear mixed models, based on an-intention-to-treat approach. The significance level will be set at 5%.
Results: The intervention will be considered successful if there is a 30% improvement in MRI parameters between pre- and post-treatment measurements, along with clinical improvement in mandibular movement.
Keywords: Temporomandibular joint disorders, anterior disc displacement, magnetic resonance imaging, musculoskeletal manipulations