Management Strategies for Heart Failure with Preserved Ejection Fraction (HFpEF): A Systematic Review and Meta-analysis
Raheel Chaudhry
Baylor College of Medicine, Houston, USA.
Arhum Mahmood
Henry Ford Health System, Detroit, USA.
Akbar Khan
HCA Oak Hill Hospital, Florida, USA.
Muhammad Sohail S. Mirza *
Shandong University School of Medicine, Jinan, China.
Rubela Ray
Bankura Sammilani Medical College, Bankura, India.
Kainat Asif
Dow Medical College, Karachi, Pakistan.
Hasher Khan
Bolan Hospital, Quetta, Pakistan.
*Author to whom correspondence should be addressed.
Abstract
Background: Heart failure with preserved ejection. Fraction is a set of clinical symptoms that raises mortality and morbidity. It should be addressed promptly and appropriately.
Aims: The current systematic review examines management strategies for heart failure patients with preserved ejection fraction (HFpEF).
Materials and Methods: PICOS scheme was followed in the development of eligibility criteria. Different databases like PubMed, Google Scholar, etc were searched for the primary studies.
Results: The final sample included 21 studies that were manually selected. This meta-analysis found that beta-blockers and ace inhibitors significantly reduced mortality and hospitalizations as primary outcomes.
Conclusion: To summarize, the study found that beta blockers and ACE inhibitors reduce mortality in heart failure patients with preserved ejection fraction. However, more research is needed to support this study.
Keywords: Management strategies, heart failure, preserved ejection fraction, inhibitors