Liposome Nano-particles for Therapeutic and Diagnostic Applications
Anil Kumar *
Department of Botany, DDU Gorakhpur University Gorakhpur-273009, India.
K. Ravishankar
KVSR, Siddhartha College of Pharmaceutical Sciences, Vijayawada, A. P, 520010, India.
Ajit Kumar Varma *
Faculty of Pharmaceutical Sciences, Rama University, Mandhana, Kanpur(U.P.),209217, India.
Deepak Prashar *
Green Hills Pharmacy College, Solan HP, India.
Jaffer Sadik Mohammed
Sri Indu Institute of Pharmacy, Sheriguda (v) Ibrahimpatnam (M) R. R. DIST-501510, India.
A. Mohathasim Billah
Department of Pharmacy Practice, Thanthai Roever College of Pharmacy,(Affiliated to Dr. MGR Medical University), Perambalur, Tamil Nadu, India.
*Author to whom correspondence should be addressed.
Abstract
LNPs mix liposomes and inorganic/ organic nanoparticles. Liposomes and nanoparticles are therapeutic. LNPs are a research tool (e.g., spatiotemporal control of drug release, hyperthermia, photothermal therapy, and biological imaging). Nanoparticles determine LNP characteristics. Nanoparticles enable liposomes overcome weak stability, few functions, and fast blood elimination. Structure, physicochemical properties, modification, and biological uses of nanoparticle materials and LNPs are reviewed.
Keywords: Liposome nanoparticles, combination therapy, controlled drug delivery system, nanostructure