Anatomical Evaluation of Mandibular Bone Cortex in Patients with Mucopolysaccharidosis: A Case-Control Study
Cledinaldo Lira Junior
Dentistry Course, State University of Paraíba, Araruna, PB, Brazil.
Diego Henrique Pires Gonçalves
Dentistry Course, State University of Paraíba, Araruna, PB, Brazil.
Kamilly de Lourdes Ramalho Frazão
Dentistry Course, State University of Paraíba, Araruna, PB, Brazil.
Sandra Aparecida Marinho
Dentistry Course, State University of Paraíba, Araruna, PB, Brazil.
Sérgio Henrique Gonçalves de Carvalho
Dentistry Course, State University of Paraíba, Araruna, PB, Brazil and Postgraduate Program of Dentistry, Federal University of Pernambuco (UFPE), Recife, PE, Brazil.
Gustavo Pina Godoy
Postgraduate Program of Dentistry, Federal University of Pernambuco (UFPE), Recife, PE, Brazil.
Fátima Roneiva Alves Fonseca
Departament of Oral Orthodontics, Federal University of Paraíba, Patos, PB, Brazil.
Dmitry José de Santana Sarmento *
Dentistry Course, State University of Paraíba, Araruna, PB, Brazil.
*Author to whom correspondence should be addressed.
Abstract
Aims: To evaluate the mandibular bone cortical of patients with mucopolysaccharidosis on panoramic radiograph, through radiomorfometric indices.
Study Design: Case-control study.
Place and Duration of Study: Sample: Department of Diagnostic Imaging of the Universidade Estadual da Paraíba, Campus VIII, in the city of Araruna, PB, between January and December of 2015.
Methodology: Panoramic radiographs of sixteen patients with mucopolysaccharidosis and 32 controls, organized by gender and age, composed the sample. The mandibular panoramic index, gonial index, antegonial index and mental index were evaluated. Pearson's Chi-square test, Fisher's exact test and Mann-Whitney test were used to statistical analysis with a level of significance of 5.0%.
Results: Mucopolysaccharidosis patients were mostly female (62.5%), with a mean age of 12.31 + 7.16 years, MPS VI (50.0%) being the most prevalent. Patients with mucopolysaccharidosis had higher values in the gonial (1.86+0.48), the antegonical (4.36+1.24) and the mental (5.24+1.21). However, only the antegoniac index presented a significant difference (P=0.047).
Conclusion: The antegoniac index was higher in patients with mucopolysaccharidosis and the other radiomorphometric measures were similar to those observed in the control group. Apparently, mucopolysaccharidosis is not related to decreased bone to mandibular quality.
Keywords: Panoramic radiography, mucopolysaccharidosis I, mucopolysaccharidosis IV, mucopolysaccharidosis VI