Comparative Study on the effect of Varicocelectomy on Infertile Patients with Normal and Low Serum Testosterone Level
Mohammed Saad Mohammed Sherif *
Department of Urology, Faculty of Medicine, Tanta University, Tanta, Egypt.
Ayman Mohammed Hagras
Department of Urology, Faculty of Medicine, Tanta University, Tanta, Egypt.
Mohammed Hassan Radwan
Department of Urology, Faculty of Medicine, Tanta University, Tanta, Egypt.
Mohammed Abo El-enen Khalwash
Department of Urology, Faculty of Medicine, Tanta University, Tanta, Egypt.
*Author to whom correspondence should be addressed.
Abstract
Introduction: Varicocele is a dilation of the pampiniform venous plexus and the internal Spermatic vein. It is detected approximately in 15% to 20 % of the general male Population; with the prevalence increasing to 40% in infertile men.
Methodology: This prospective, comparative study was conducted on 134 male patients with primary infertility who attended the outpatient clinic of Urology Department, Tanta University Hospital during the period between April 2017 to April 2019. The patients were divided into two groups: Group A (56 patients) with low testosterone level. Group B (78 patients) with normal testosterone level.
Results: In group A, the mean ± SD of testosterone level improved significantly to 2.93 ± 0.77 and 3.36 ± 0.86 after 3 and 6 months respectively (p1-value=0.001* and p2-value=0.001* respectively). In group B, the mean ± SD of testosterone level improved significantly to 6.22 ± 1.51 and 6.82 ± 2.25 after 3 and 6 months respectively (p1-value=0.026* and p2-value=0.001* respectively).
Conclusion: varicocelectomy could improve semen parameters, serum testosterone level and pregnancy rate.
Keywords: Infertile, testosterone, varicocele, varicocelectomy