Relationship between Toxoplasma Gondii and Psychotic Disorders with Implications toward a Brain-based Diagnostic System and Novel Treatment Approaches: A Study Protocol
Dina Raja
Department of Microbiology, Gauhati Medical College Hospital, Guwahati, Assam, India.
Shyamanta Das *
Department of Psychiatry, Gauhati Medical College Hospital, Guwahati, Assam, India.
Chimanjita Phukan
Department of Microbiology, Assam Medical College Hospital, Dibrugarh, Assam, India.
Simanta Talukdar
Department of Psychiatry, Assam Medical College Hospital, Dibrugarh, Assam, India.
Samrat Singh Bhandari
Department of Psychiatry, Sikkim Manipal Institute of Medical Sciences, Gangtok, Sikkim, India.
Naba Kumar Hazarika
Hindlabs centres, HLL Lifecare Ltd, Assam CM’s Free Lab Diagnostic Service Project, India.
Dipesh Bhagabati
Department of Psychiatry, Agartala Govt. Medical College & G.B. Pant Hospital, Agartala, Tripura, India.
*Author to whom correspondence should be addressed.
Abstract
What role infectious agents play in the causation of psychotic disorders? To investigate this area, we have aimed to investigate the relationship between Toxoplasma gondii and psychotic disorders. A hospital-based cross-sectional study is designed. IgM and IgG antibodies to T. gondii in patients with psychotic disorders will be measured and presented in result. Seropositivity rates will be compared with first-degree relatives and healthy volunteers. Also, types of psychotic disorders and seropositivity rate will be compared. Here, we are presenting the study protocol with implications toward a brain-based diagnostic system and novel treatment approaches.
Keywords: Toxoplasma gondii, psychotic disorders, diagnostic system, seropositivity rate