The Relationship between Procalcitonin with Morbidity, Mortality and Survival in Gastric Cancer
Mehmet Ali Çaparlar
Surgical Oncology Clinic, School of Medicine, Ankara University, Ankara, Turkey.
Yasin Uçar
General Surgery Clinic, Ankara City Hospital, University of Health Sciences, Ankara, Turkey.
Şeref Dokcu
Surgical Oncology Clinic, School of Medicine, Ankara University, Ankara, Turkey.
Ismail Hasirci
General Surgery Clinic, Konya City Hospital, University of Health Sciences, Konya, Turkey.
Mehmet Eşref Ulutaş *
General Surgery Clinic, Konya City Hospital, University of Health Sciences, Konya, Turkey.
Ogün Erşen
General Surgery Clinic, Konya City Hospital, University of Health Sciences, Konya, Turkey.
*Author to whom correspondence should be addressed.
Abstract
Introduction: In this study, it was aimed to examine the relationship between procalcitonin (PCT) values and complications, age, mortality, survival and to evaluate the correlation of procalcitonin, C-reactive protein (CRP), and white blood cell (WBC) values in patients operated for gastric cancer.
Methods: File records of 50 patients who were operated on for gastric cancer between 2015 and 2018 and whose procalcitonin levels were obtained were retrospectively reviewed.
Results: Eighteen (36%) of the study participants in the study were female, and 32 (64%) were male. Mortality rates were found to be significantly higher in those with PCT values of 2 and above on PO 1st and 3rd days. It was observed that the development of respiratory complications was significantly higher in patients with a PCT value of 2 and above on PO 5th and 7th days.
Conclusions: Post-operative high values in gastric cancer patients are significant in terms of mortality and survival in the follow-up. In gastric cancer and other malignant diseases, it is necessary to determine cut-off values, to conduct specificity and sensitivity studies by making detailed examinations for respiratory complications, mortality, and survival times during treatment.
Keywords: Gastric cancer, cancer-related deaths, morbidity, hospitalization, procalcitonin