Magnetic Resonance Imaging (MRI) Double Inversion Recovery Sequence in Diagnosis of Multiple Sclerosis
Ahmed Samir Ghonim
*
Diagnostic Radiology, Faculty of Medicine, Tanta University, Egypt.
Rasha Lotfy Younes
Diagnostic Radiology, Faculty of Medicine, Tanta University, Egypt.
Mohamed Amin Mohamed
Diagnostic Radiology, Faculty of Medicine, Tanta University, Egypt.
Mohamed Fathy Dawoud
Diagnostic Radiology, Faculty of Medicine, Tanta University, Egypt.
*Author to whom correspondence should be addressed.
Abstract
Aims: The current work aimed to assess the diagnostically value of Magnetic Resonance Imaging (MRI) Double Inversion Recovery (DIR) sequence in diagnosing of multiple sclerosis.
Methodology: This study conducted on (42 patients) from the Diagnostic Radiology and Medical Imaging Dep. at Tanta University Hospital in the period from March 2018 to December 2019.
Results: In accordance to the total lesions loads, it was found that DIR was higher significantly than T2WI (P-value= 0.003 with a relative gaining of 22%), we found that double inversion recovery (DIR) sequence was higher significantly to FLAIR regarding the number of diagnosed lesions in 3 anatomical areas (Mixed W-GM, cortical and infra-tentorial) with relative gaining of 28%, 85% and 63% respectively. A non-significant change was found among the two sequences regarding peri-ventricular white matter, deep white matter and juxta-cortical lesions detecting.
Conclusion: Conventionally MRI has corner-stone roles in diagnosing, characterizing and following-up of multi-sclerosis. Finally, we concluded that DIR can be used as a addition to or even as an alternative for typical T2 and FLAIR. Therefore, we strongly recommend the addition of DIR sequences in the everyday MR protocol of MS cases.
Keywords: Double inversion recovery, conventional, magnetic resonance imaging, multiple sclerosis.