Morphofunctional Changes in Basophilic Cells of the Adenohypophysis during Post-resuscitation Disease

Aminjon Gadaeyevich Karabayev *

Department of Pathological Physiology, Samarkand Medical Institute, Republic of Uzbekistan.

Rajabboy Isroilovich Isroilov

Center of Pathological Anatomy, Ministry of Health, Republic of Uzbekistan.

*Author to whom correspondence should be addressed.


Abstract

In the post-resuscitation period through the I-II-III-IV-V - stages and long - term periods (1 and 3 months) of post – resuscitation disease, the morpho functional activity of β-and d-basophil cells of the adenohypophysis was studied in white male rats with a weight of 180-220 g, who suffered a 10-minute stop of systemic circulation (compression of the vascular bundle of the heart by the method of V. G. Korpachev). False-operated animals served as a control. Morphological, morphometric, histochemical, and cytophotometric studies of the state of both β - and d - basophil cells of the adenohypophysis were performed. We used image analysis using a leys microscope with an electronic micro-nozzle attached to an Intel computer, and the content of the glycoprotein was studied using a cytophotometer. In the postoperative period during the phase I identified in the background of gipergidratace cytoplasmic β - and d - basophilic cells of the anterior pituitary, in the period of II-III stage disease gipergidratace nuclei β - and d - basophilic cells of the anterior pituitary revealed an increase in the excretion of glycoprotein in blood, i.e., the observed compensatory-adaptive reactions. Starting from stage IV and in remote periods of post-resuscitation disease, compensatory and restorative processes were observed against the background of hyperhydration of the nuclei.

Keywords: Clinical death, post-resuscitation period, basophilic cells, adenohypophysis, glycoprotein


How to Cite

Karabayev, Aminjon Gadaeyevich, and Rajabboy Isroilovich Isroilov. 2020. “Morphofunctional Changes in Basophilic Cells of the Adenohypophysis During Post-Resuscitation Disease”. Journal of Advances in Medicine and Medical Research 32 (8):130-35. https://doi.org/10.9734/jammr/2020/v32i830473.

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