Mandibular Osteomyelitis in Concurrence with Psoriasis: A Rare Case Report and Literature Review
Hong He *
Stomatology Hospital, School of Medicine, Zhejiang University, Hangzhou, China and Key Laboratory of Oral Biomedical Research of Zhejiang Province, Hangzhou, China.
Xinyu Xia
Stomatology Hospital, School of Medicine, Zhejiang University, Hangzhou, China and Key Laboratory of Oral Biomedical Research of Zhejiang Province, Hangzhou, China.
Jinhan Zhou
Stomatology Hospital, School of Medicine, Zhejiang University, Hangzhou, China and Key Laboratory of Oral Biomedical Research of Zhejiang Province, Hangzhou, China.
Xiaotong Deng
Stomatology Hospital, School of Medicine, Zhejiang University, Hangzhou, China and Key Laboratory of Oral Biomedical Research of Zhejiang Province, Hangzhou, China.
Kejie Lu
Stomatology Hospital, School of Medicine, Zhejiang University, Hangzhou, China and Key Laboratory of Oral Biomedical Research of Zhejiang Province, Hangzhou, China.
Er Li
Haishu Stomatology Hospital, Ningbo, China.
Qingzhu Wu
Haishu Stomatology Hospital, Ningbo, China.
*Author to whom correspondence should be addressed.
Abstract
Mandibular osteomyelitis in a patient with psoriasis is an uncommonly clinical manifestation while there is an increasing number of reports and studies on involvements of stomatology in psoriasis, especially the death of a patient via or not via Allogeneic bone marrow transplantation has never been reported. To review the management and possible mechanisms in pathogenesis and treatment of psoriasis, as well as the relative involvements between stomatology and psoriasis the typical case with pictures and files is reviewed and literature is collected.Wekeepthe knowledge that psoriasis is either a primary keratinocyte disorder or an immunocyte-mediated chronic skin inflammatory disease while bone marrow is under suspected for immunopathogenesis. More association of stomatologic conditions with psoriasis is emerging. Conclusively, allogeneic BMT and new knowledge are worth to be stressed by both stomatological and dermatological doctors. Further insights of this kind of auto immunologic disease are under its developing.
Keywords: Psoriasis, immunopathogenesis, keratinocyte disorder, osteomyelitis.