Uterine Leiomyosarcoma: A Case Report and Review of Relevant Literatures
A. J. Omotoso
Department of Pathology, University of Calabar, Calabar, Nigeria.
P. O. Odusolu
Department of Obstetrics and Gynaecology, University of Calabar, Calabar, Nigeria.
M. A. Nnoli
Department of Pathology, University of Calabar, Calabar, Nigeria.
E. L. Ekpe *
Department of Chemical Pathology, University of Calabar, Calabar, Nigeria.
K. Omoruyi
Department of Pathology, University of Calabar, Calabar, Nigeria.
*Author to whom correspondence should be addressed.
Abstract
Leiomyomas are benign soft tissue neoplasms that arise from smooth muscles. Leiomyosarcoma is a malignant lesion of smooth muscle origin. This is a rare lesion in the uterus with 1-2 % of its benign counterpart, leiomyoma, transforming into the lesion. It is often aggressive and could develop at any site where the smooth muscle is found. We present a case of a 48-year-old farmer with pelvic mass with Ultra-sonography(USS) suggestive of leiomyoma. Hysterectomy was done and histologic diagnosis of leiomyosarcoma (LMS) was made. The patient was discharged 7 days post operation but was lost to follow up. Uterine LMS is an aggressive tumour, therefore, a high index of suspicion is needed especially for huge uterine nodules and such patients must be closely monitored for adequate management.
Keywords: Uterus, leiomyosarcoma, smooth muscle.