Magnetic Resonance Imaging (MRI) Double Inversion Recovery Sequence in Diagnosis of Multiple Sclerosis
Journal of Advances in Medicine and Medical Research,
Aims: The current work aimed to assess the diagnostically value of Magnetic Resonance Imaging (MRI) Double Inversion Recovery (DIR) sequence in diagnosing of multiple sclerosis.
Methodology: This study conducted on (42 patients) from the Diagnostic Radiology and Medical Imaging Dep. at Tanta University Hospital in the period from March 2018 to December 2019.
Results: In accordance to the total lesions loads, it was found that DIR was higher significantly than T2WI (P-value= 0.003 with a relative gaining of 22%), we found that double inversion recovery (DIR) sequence was higher significantly to FLAIR regarding the number of diagnosed lesions in 3 anatomical areas (Mixed W-GM, cortical and infra-tentorial) with relative gaining of 28%, 85% and 63% respectively. A non-significant change was found among the two sequences regarding peri-ventricular white matter, deep white matter and juxta-cortical lesions detecting.
Conclusion: Conventionally MRI has corner-stone roles in diagnosing, characterizing and following-up of multi-sclerosis. Finally, we concluded that DIR can be used as a addition to or even as an alternative for typical T2 and FLAIR. Therefore, we strongly recommend the addition of DIR sequences in the everyday MR protocol of MS cases.
- Double inversion recovery
- magnetic resonance imaging
- multiple sclerosis.
How to Cite
Polman CH, Reingold SC, Edan G. Diagnostic criteria for multiple sclerosis: Revisions to the “McDonald Criteria”. Ann Neurol. 2005;58:840–4.
Bakshi R, Ariyaratana S, Benedict RH. Fluid-attenuated inversion recovery magnetic resonance imaging detects cortical and juxta-cortical multiple sclerosis lesions. Arch Neurol. 2001;58:742–48.
Simon JH, Li D, Traboulsee A. Standardized MR imaging protocol for multiple sclerosis: Consortium of MS centers consensus guidelines. AJNR Am J Neuroradiol. 2006;27:455–61.
Frohman EM, Zhang H, Kramer PD. MRI characteristics of MLF in MS patients with chronic inter nuclear ophthalmoparesis. Neurology. 2001;57:762–68.
Cotton FR, ambaud L, Hermier M, Dual inversion recovery MRI helps identifying cortical tubers in tuberous sclerosis. 2006; 47(6):1072- 1073.
Simon B, Schmidt S, Lukas C. Improved in vivo detection of cortical lesions in multiple sclerosis using double inversion recovery MR imaging at 3 Tesla. European radiology. 2010;20:1675-1683.
Frischer JM, Weigand SD, Guo Y. Clinical and pathological insights into the dynamic nature of the white matter multiple sclerosis plaque. Annals of neurology. 2015;78:710-721.
Geurts JJG, Pouwels PJW, Uitdehaag BMJ. Intracortical Lesions in Multiple Sclerosis: Improved detection with 3D double inversion-recovery MR imaging. Radiology. 2005;236:254-260.
Thompson AJ, Banwell BL, Barkhof F. Diagnosis of multiple sclerosis: Revisions of the McDonald criteria. Lancet Neurol. 2017;69:60-78.
Abidi Z, Faeghi F, Mardanshahi Z. Assessment of the diagnostic accuracy of double inversion recovery sequence compared with FLAIR and T2W_TSE in detection of cerebral multiple sclerosis lesions. Electron Physician. 2017;9:4162-4170.
Elnekeidy AM, Kamal MA, Elfatatry AM. Added value of double inversion recovery magnetic resonance sequence in detection of cortical and white matter brain lesions in multiple sclerosis. The egyptian journal of radiology and nuclear medicine. 2014;45:1193-1199.
Wattjes MP, Lutterbey GG, Gieseke J. Double Inversion Recovery Brain Imaging at 3T: Diagnostic value in the detection of multiple sclerosis lesions. American Journal of Neuroradiology. 2007;28:54-59.
Vural G, Keklikoglu HD, Temel S. Comparison of double inversion recovery and conventional magnetic resonance brain imaging in patients with multiple sclerosis and relations with disease disability. Neuroradiol J. 2013;26:133-142.
Moraal B, Roosendaal SD, Pouwels PJ. Multi-contrast, isotropic, single-slab 3D MR imaging in multiple sclerosis. Eur Radiol. 2008;18:2311-2320.
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