Pre-Interventional and Post-Interventional Analysis of Knowledge, Attitude and Practice Regarding Hepatitis B & C among Prison Inmates of Malir Jail, Karachi, Pakistan

Main Article Content

Agha M. Wali Mirza
Syed Ali Farhan
Junaid Nawab
Sahrish Mukhtar
Shagufta Naqvi
Syed Sanower Ali
Iqra Baig
Mohid Ahmad
Wassay Hussain


Background: Hepatitis B and Hepatitis C being the most prevalent and preventable infectious disease in Sindh with prison inmates being a major risk group.

Aims: To assess the knowledge, attitude and practice of this deadly debilitating disease.

Study Design: Interventional Study

Place and Duration of Study: It was performed in Malir Jail, Karachi, Pakistan in which 128 prison inmates participated. The research was done in three phases for the duration of 1 month.

Methodology: In first phase a pre-intervention questionnaire was filled which assessed the basic knowledge regarding hepatitis, its spread and prevention. In the second phase an elaborate audiovisual presentation was given with detailed explanation to all the participants about hepatitis B and hepatitis C. In the third phase a post-intervention questionnaire was filled.

Results: On assessment, the results showed that before intervention prisoners lacked basic knowledge about hepatitis and after the intervention their knowledge and awareness improved significantly with a p-value of <0.001.

Conclusion: It is concluded that prison inmates of Malir jail Karachi lacked basic knowledge of hepatitis B and hepatitis C and with substantial repeated interventions this preventable infectious disease could be prevented.

Intervention, Karachi prison, Hepatitis B, Hepatitis C, spread, prevention

Article Details

How to Cite
Mirza, A. M. W., Farhan, S. A., Nawab, J., Mukhtar, S., Naqvi, S., Ali, S. S., Baig, I., Ahmad, M., & Hussain, W. (2020). Pre-Interventional and Post-Interventional Analysis of Knowledge, Attitude and Practice Regarding Hepatitis B & C among Prison Inmates of Malir Jail, Karachi, Pakistan. Journal of Advances in Medicine and Medical Research, 32(24), 89-99.
Original Research Article


Hakim S, Kazmi S, Bagasra O. Seroprevalence of hepatitis B and C genotypes among young apparently healthy females of Karachi-Pakistan. Libyan Journal of Medicine. 2008;3(2):66-70.

Noorali S, Hakim ST, McLean D, Kazmi SU, Bagasra O. Prevalence of Hepatitis B virus genotype D in females in Karachi, Pakistan. The Journal of Infection in Developing Countries. 2008;2(05):373-8.

Al Kanaani Z, Mahmud S, Kouyoumjian SP, Abu-Raddad LJ. The epidemiology of hepatitis C virus in Pakistan: Systematic review and meta-analyses. Royal Society Open Science. 2018;5(4):180257.

Bick JA. Infection control in jails and prisons. Clinical Infectious Diseases. 2007; 45(8):1047-55.

Niveau G. Prevention of infectious disease transmission in correctional settings: A review. Public health. 2006;120(1):33-41.

Gahrton C, Westman G, Lindahl K, Öhrn F, Dalgard O, Lidman C, et al. Prevalence of Viremic hepatitis C, hepatitis B, and HIV infection, and vaccination status among prisoners in Stockholm County. BMC Infectious Diseases. 2019; 19(1):955.

Moradi G, Jafari S, Zarei B, Mahboobi M, Azimian Zavareh F, Molaeipoor L, et al. Prevalence and risk factors for Hepatitis B and Hepatitis C Exposure in Iranian Prisoners: A national study in 2016. Hepatitis Monthly. 2019;19(7).

Gorar ZA, Zulfikar I. Seropositivity of hepatitis C in prison inmates of Pakistan--a cross sectional study in prisons of Sindh. J Pak Med Assoc. 2010;60(6):476-9.

Amir M, Rahman AS, Ahmed S, Siddiqui MA, Jamal Q, editors. Seroprevalence of HCV, HBV and HIV in the male prisoners at central jail, Karachi. Med Forum; 2016.

Kazi AM, Shah SA, Jenkins CA, Shepherd BE, Vermund SH. Risk factors and prevalence of tuberculosis, human immunodeficiency virus, syphilis, hepatitis B virus, and hepatitis C virus among prisoners in Pakistan. International Journal of Infectious Diseases. 2010;14:e60-e6.

Zampino R, Coppola N, Sagnelli C, Di Caprio G, Sagnelli E. Hepatitis C virus infection and prisoners: Epidemiology, outcome and treatment. World Journal of Hepatology. 2015;7(21):2323.

Shahid A, Pirzada AG, Memon AA. Knowledge and educational intervention pertaining to viral hepatitis in adolescent male students of urban and rural Sindh, Pakistan. Journal of Dow University of Health Sciences. 2013;6(2).

Khan A, Ali M. Knowledge and attitude regarding Hepatitis-B prevention among people of Lahore community, Pakistan. International Journal of Social Sciences and Management. 2017;4(1):68-76.

Wali A, Khan D, Safdar N, Shawani Z, Fatima R, Yaqoob A, et al. Prevalence of tuberculosis, HIV/AIDS, and hepatitis; In a prison of Balochistan: A cross-sectional survey. BMC public health. 2019;19(1):1-8.

Dana D, Zary N, Peyman A, Behrooz A. Risk prison and hepatitis B virus infection among inmates with history of drug injection in Isfahan, Iran. The Scientific World Journal; 2013.

Mehmood S, Raza H, Abid F, Saeed N, Rehan HM, Javed S, et al. National prevalence rate of hepatitis B and C in Pakistan and its risk factors. Journal of Public Health. 2019;1-14.

Krisnuhoni E. Prevalence of hepatitis virus infection in prisoners. The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy. 2019;20(1):1.

Qadeer MI, Aslamkhan M, Akhtar MS, Ellahi F. Pre-blood-donation screening of volunteer prisoners for hepatitis B and C in prisons of the Punjab, Pakistan. Acta Medica International. 2016; 3(2):31.

Connoley D, Francis‐Graham S, Storer M, Ekeke N, Smith C, Macdonald D, et al. Detection, stratification, and treatment of hepatitis C positive prisoners in the United Kingdom prison estate: Development of a pathway of care to facilitate the elimination of hepatitis C in a London prison. Journal of Viral Hepatitis; 2020.

Jack K, Linsley P, JamesThomson B, Irving WL. How do people in prison feel about opt‐out hepatitis C virus testing? Journal of Viral Hepatitis; 2020.

Crowley D, Murtagh R, Cullen W, Keevans M, Laird E, McHugh T, et al. Evaluating peer-supported screening as a hepatitis C case-finding model in prisoners. Harm Reduction Journal. 2019; 16(1):42.