A Case of Diffuse Pulmonary Calcification with Multiple Myeloma
Ya-Wen Chuang
Department of Nuclear Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
Chien-Chin Hsu
Department of Nuclear Medicine, Kaohsiung Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taiwan
Chin-Chuan Chang
Department of Nuclear Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
Chia-Yang Lin
Department of Nuclear Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan and Department of Medical Imaging and Radiological Sciences, College of Health Science, Kaohsiung Medical University, Kaohsiung, Taiwan
Ying-Fong Huang
Department of Nuclear Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan and Department of Medical Imaging and Radiological Sciences, College of Health Science, Kaohsiung Medical University, Kaohsiung, Taiwan
Yu-Chang Tyan *
Department of Medical Imaging and Radiological Sciences, College of Health Science, Kaohsiung Medical University, Kaohsiung, Taiwan and Center for Infectious Disease and Cancer Research, Kaohsiung Medical University, Kaohsiung, Taiwan and Institute of Medical Science and Technology, National Sun Yat-sen University, Kaohsiung, Taiwan and Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan and Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
*Author to whom correspondence should be addressed.
Abstract
A 40 year old male with a 4-year history of multiple myeloma (MM) had recurrent episodes of extensive bone involvement. A 99mTc-MDP bone scan revealed unusual radiotracer accumulations within bilateral pulmonary fields. There was no radiographic evidence of calcification in the lungs. It may represent metastatic pulmonary calcification and can be clinically correlated with hypercalcemia in MM.
Keywords: Bone scan, hypercalcemia, calcification, multiple myeloma