Arterial Blood Flow and its Association with BMI in Hypertensive Adult Male Subjects under Resting State
A. A. Aigbiremolen *
Department of Pharmacology and Therapeutics, Faculty of Clinical Sciences, College of Medicine, Ambrose Alli University, Ekpoma, Edo State, Nigeria.
P. R. C. Esegbue
Department of Physiology, Faculty of Basic Medical Sciences, College of Medicine, Olabisi Onabanjo University, Sagamu, Ogun State, Nigeria.
R. E. Ubom
Department of Human Physiology, College of Medicine, University of Nigeria, Enugu Campus, Enugu State, Nigeria.
O. M. Odigie
Department of Human Physiology, Faculty of Basic Medical Sciences, College of Health Sciences, Delta State University, Abraka, Delta State, Nigeria.
I. O. Iribhogbe
Department of Pharmacology and Therapeutics, Faculty of Clinical Sciences, College of Medicine, Ambrose Alli University, Ekpoma, Edo State, Nigeria.
C. P. Aloamaka
Department of Human Physiology, Faculty of Basic Medical Sciences, College of Health Sciences, Delta State University, Abraka, Delta State, Nigeria.
*Author to whom correspondence should be addressed.
Abstract
The goal of this study was to determine the association between arterial blood flow in normal and high BMI of hypertensive adult male subjects under resting state. To achieve this, 400 humans were ethically recruited from Irrua Specialist Teaching hospital, Irrua, Edo State of Nigeria. Subjects were sorted by age and grouped based on values from blood pressure readings as; 120 normotensive normal BMI (120-NNBMI), 120 normotensive high BMI (120-NHBMI), 80 hypertensive normal BMI (80-HNBMI), and 80 hypertensive high BMI (80-HHBMI). For the arterial blood flow at day time before noon of non-fasting subjects, left brachial arteries were measured in cm/s. At interval of five minutes, procedure was repeated three times with average taken. Subjects were then grouped as normotensive or hypertensive based on the average systolic and diastolic blood pressure values (120/80 mmHg or 140/90 mmHg, respectively). Body mass index was determined by weight-to-height ratio (kg/m2). Mean values of weight, height, BMI, blood pressure (BP) and arterial blood flow were determined and expressed as mean ± standard error of mean (SEM). Obtained data was then analysed using ANOVA. P values less than 0.05 was the basis for significance. Pearson Product Moment Correlation Coefficient was used for statistical measurements of association. In the end, there was a significant negative correlation between arterial blood flow and BMI in hypertensive subjects. Whereas, normotensive subjects show insignificant correlation.
Keywords: Normotensives, hypertensives, blood pressure, body mass index, arterial blood flow