Maxillary Clear Cell Odontogenic Carcinoma - A Rare Entity
T. L. Yogesh
Department of Oral and Maxillofacial Pathology, Sri Rajiv Gandhi College of Dental Sciences and Hospital, Cholanagar, Hebbal, Bangalore-560032, Karnataka, India.
Hema Keswani *
Department of Oral and Maxillofacial Pathology, Sri Rajiv Gandhi College of Dental Sciences and Hospital, Cholanagar, Hebbal, Bangalore-560032, Karnataka, India
Akshay Shetty
Department of Oral and Maxillofacial Surgery, Sri Rajiv Gandhi College of Dental Sciences and Hospital, Bangalore-560032, Karnataka, India.
Hemavathy S
Department of Oral and Maxillofacial Pathology, Sri Rajiv Gandhi College of Dental Sciences and Hospital, Cholanagar, Hebbal, Bangalore-560032, Karnataka, India.
*Author to whom correspondence should be addressed.
Abstract
Clear cell odontogenic carcinoma (CCOC) is a rare odontogenic tumor with predominance in the posterior mandible, usually occurring in the fifth to seventh decades of life, and being found more commonly in females. It is a potentially aggressive tumour, capable of recurring frequently, locally invasive, and with distant metastases. Here we report a case of clear cell odontogenic carcinoma of maxilla in a 70 years old female, with a tumor mass on right side of the palate in the premolar - molar region. Microscopically, biphasic population of cells with characteristic polygonal, clear cells, hyperchromatic and basaloid cells with eosinophillic cytoplasm were seen. There was positive immunoreactivity with markers Ki67 and cytokeratin CK19. The significance of histochemical and immunohistochemical resources in the correct diagnosis of CCOC is presented.
Keywords: Clear cell odontogenic carcinoma, clear cell, maxilla