Journal of Advances in Medicine and Medical Research

Background and Objectıves: To evaluate changes in eyes with idiopathic parafoveal telangiectasia  type 2 (IPFT) using  spectral domain optical coherence tomography (SD-OCT).

Materıals and Methods: SD-OCT images of cases  were analyzed for the presence or absence of foveal contour asymmetry, inner and outer retinal cavities, hyperreflective spots, photoreceptor disruption and outer limiting membrane (OLM) integrity.

Results: Twelve eyes of 7 patients with IPFT type 2 were examined by SD-OCT. Foveal contour asymmetry was found in 41.6% of the eyes. Hyporeflective retinal cavities were found in 25% involving only inner layer, 8.3% involving only outer layer and 66.6%  involving both inner and outer layers of the eyes. In 50% of the eyes, hyperreflective spots were present. Photoreceptor loss was observed in 66.6% of the eyes and appeared as hyporeflective areas at inner and outer photoreceptor segments (IS-OS) junction. Of the 8 eyes with photoreceptor disruption, the OLM was disrupted in 7 eyes (87.5%). OLM was intact in all 3 eyes with only inner retinal layer  cavitation. The all eyes with both inner and outer retinal cavities had photoreceptor disruption.

Conclusıon: This study desribed characteristic changes in IPFT type 2 based on SD-OCT. The pathogenesis of IPFT type 2 is not entirely understood and SD-OCT is a powerful tool for evaluating this disorder. According to our findings, the integrity of both OLM and photoreceptors seem to be closely associated with IPFT type 2 and  the primary pathology in these eyes is the Müller cells.