Therapeutic of Controlled Exposure to Selected Allergens - A Non-drug Measure
Nwachukwu Francis Chukwuedozie *
Department of Biochemistry and Forensic Science, Faculty of Science, Nigeria Police Academy, Nigeria.
O. Mbakwe
Department of Laboratory, General Hospital Kubwa, Abuja, Nigeria.
Onwuegbule Martina Chinyere
Intensive Care Unit, Federal Medical Center, Owerri, Imo State, Nigeria.
*Author to whom correspondence should be addressed.
Abstract
Allergies exemplify the cases in which normally unnecessary immune responses give rise to diseases. The research was aimed to explain some of the background on biochemical adaptation, in non drug treatment of allergic reactions through well-thought-out exposure on allergens. Allergic reactions viz: Insect sting allergy, allergic rhinitis, food allergy, drug allergy and allergic asthma were delved into and result presented in percentage reliability. The results of the six-year showed insect sting allergy, allergic asthma, and allergic rhinitis were 60, 33 and 39% respectively, while drug and food allergy were 30 and 38% respectively. The allergies follow similar pattern in all, involving inflammation, immunoglobulin E, histamine among others. The results depicted that controlled repetitive exposures caused desensitization and tolerance to the respective allergens. This method might have reduced the production of allergic participatory cells hence a new form of vaccination. This study described the outcome of the association between allergen exposure, sensitization and allergic diseases. This work is considered paramount when allergy symptoms are moderate to severe, occurs throughout the year, do not respond adequately to medications, and are triggered by an allergen not easily avoided.
Keywords: Allergic reaction, desensitization, tolerance, reliability, triggers