Seroprevalence of Hepatitis B and C Viruses amongst Type 2 Diabetic Patients in Dutse, Jigawa State, Nigeria
Bako Hauwa *
Chemical Pathology Unit, Department of Medical Laboratory Sciences, Rasheed Shekoni Specialist Hospital, Dutse, Jigawa State, Nigeria.
Muazu, Salisu Babura
Department of Internal Medicine, Rasheed Shekoni Specialist Hospital, Dutse, Jigawa State, Nigeria.
Dankoly, Sani Usman
Department of Physiotherapy, Dutse General Hospital, Jigawa State, Nigeria.
Ahmad, Mohammad Bello
Chemical Pathology Unit, Department of Medical Laboratory Sciences, Faculty of Allied Health Sciences, College of Health Sciences, Bayero University, Kano, Nigeria.
Iliya Sani
Healthwise Diagnostic Laboratories Ltd., 100 Amasalco Plaza, Zoo Road, Kano State, Nigeria.
John, Noah Onuche
Hematology Unit, Department of Medical Laboratory Sciences, Rasheed Shekoni Specialist Hospital, Dutse, Jigawa State, Nigeria.
Mustapha, Aminu Saleh
Hematology Unit, Department of Medical Laboratory Sciences, Rasheed Shekoni Specialist Hospital, Dutse, Jigawa State, Nigeria.
Banya, Richard James
Department of Medical Laboratory Sciences, College of Health Technology, Takum, Taraba State, Nigeria.
*Author to whom correspondence should be addressed.
Abstract
Introduction: Viral hepatitis is a liver disease with numerous etiologies. Hepatitis B and C virus infections and co infections are pandemics that constitute a major public health challenge in Nigeria. Diabetes mellitus is sought to be a risk factor for HBsAg and HCV coexistence. The study was aimed at estimating the seroprevalence of HBsAg and HCV viruses amongst type 2 diabetic patients in Dutse Jigawa State, Nigeria.
Methods: The study was randomized and cross sectional conducted amongst type 2 diabetics. A total of 192 consecutive type 2 diabetes mellitus patients attending the endocrine clinic and 120 age and sex matched apparently healthy volunteers who consented to participate in the study were recruited. All the participants were screened for HBsAg and HCV using immunochromatographic test kits and confirmed by ELISA technique for seropositive cases.
Results: Prevalence rates of HBsAg was equal 9(4.68%) for the type 2 diabetics and controls while that of Anti-HCV was 3(1.56%) and 1(0.52%) in the type 2 diabetics and controls (p≤0.05) respectively. Co infection was recorded in the control subjects but not in the diabetes group.
Conclusion: There is a statistical significant association between HCV and type 2 diabetes mellitus with the seropositivity of HCV 3.0 times higher in type 2 diabetic patients compared to healthy controls.
Keywords: Diabetes mellitus, hepatitis B, hepatitis C, prevalence, Jigawa, Nigeria