Effects of Initial Periodontal Treatment in Moderately Compensated and Decompensated Type 2 Diabetic Patients
Paula Bernardon
Department of Dental Clinics, State University of West Parana (UNIOESTE), Cascavel, Parana, Brazil.
Gisele Toyama
Department of Biosciences and Health, State University of West Parana (UNIOESTE), Cascavel, Parana, Brazil.
Karine Figueredo da Costa
Department of Dental Clinics, State University of West Parana (UNIOESTE), Cascavel, Parana, Brazil.
Bruno Marques Sbardelotto
Department of Oral and Maxillo Facial Surgery, State University of West Parana (UNIOESTE), Cascavel, Paraná, Brazil.
Carlos Alberto Garcia Junior
State University of West Parana (UNIOESTE), Cascavel, Parana, Brazil.
Muriel Machado Marquez Zampiva
Academic of Dentistry Course, State University of West Parana (UNIOESTE), Cascavel, Parana, Brazil.
Marcela Chiqueto Araújo
State University of West Parana (UNIOESTE), Cascavel, Parana, Brazil.
Jéssica Cristiane Michelin Mânica
State University of West Parana (UNIOESTE), Cascavel, Parana, Brazil.
Carlos Augusto Nassar
Periodontics Course, State University of West Parana (UNIOESTE), Cascavel, Paraná, Brazil.
Patricia Oehlmeyer Nassar *
Periodontics Course, State University of West Parana (UNIOESTE), Cascavel, Paraná, Brazil.
*Author to whom correspondence should be addressed.
Abstract
Objective: The objectives of this research were to evaluate the effect of periodontal therapy in moderately compensated and decompensated type 2 diabetic patients.
Materials and Methods: 20 patients with type 2 diabetes mellitus (DM2) and periodontal disease were selected and divided into two groups (based on HbA1c level): Group 1: Moderately compensated; Group 2: Decompensated. The analyses including clinical periodontal parameters and the quantification of gingival crevicular fluid (GCF), the IL1-β expression in the GCF and Glycated hemoglobin (HbA1c) and fasting glucose (FG) from venous blood were performed at 0, 3, and 6 months.
Results: Both groups presented improvement in all clinical periodontal parameters as well as quantification of gingival crevicular fluid and in the expression of IL-1ß present in the fluid after 6 months. However, no statistically significant difference was found in the levels of HbA1C in the group 1 after 6 months, although a significant increase was found after six months in the group 2. While in relation to the FG, a great improvement was found in the group 1 and a significant increase in the group 2 after six months.
Conclusions: It was possible to observe that conventional periodontal treatment (scaling and root planning) is more effective for moderately compensated type 2 diabetic patients’ glycemic control rather than for the decompensated patients.
Keywords: Diabetes mellitus, gingival crevicular fluid, periodontal disease, glycemic control.