Ileo-ileal Intussusception Caused by Primary Monophasic Synovial Sarcoma (SS) of the Ileum
Ernesto Di Cesare *
Department of Biotechnology and Applied Clinical Sciences, Division of Radiotherapy and Cardiac Radiology, San Salvatore Hospital, University of L’Aquila, L. Natali Street 1, 67100 L’Aquila, Italy
Irene Amicarelli
Department of Biotechnology and Applied Clinical Sciences, Division of Radiology, San Salvatore Hospital, University of L’Aquila, L. Natali Street 1, 67100 L’Aquila, Italy
Alessandra Di Sibio
Department of Biotechnology and Applied Clinical Sciences, Division of Radiology, San Salvatore Hospital, University of L’Aquila, L. Natali Street 1, 67100 L’Aquila, Italy
Antonio Gennarelli
Department of Biotechnology and Applied Clinical Sciences, Division of Radiology, San Salvatore Hospital, University of L’Aquila, L. Natali Street 1, 67100 L’Aquila, Italy
Valentina Felli
Department of Biotechnology and Applied Clinical Sciences, Division of Radiology, San Salvatore Hospital, University of L’Aquila, L. Natali Street 1, 67100 L’Aquila, Italy
Valentina Vellucci
Department of Biotechnology and Applied Clinical Sciences, Division of Radiology, San Salvatore Hospital, University of L’Aquila, L. Natali Street 1, 67100 L’Aquila, Italy
Marco Perri
Department of Biotechnology and Applied Clinical Sciences, Division of Radiology, San Salvatore Hospital, University of L’Aquila, L. Natali Street 1, 67100 L’Aquila, Italy
Claudia Marsecano
Department of Biotechnology and Applied Clinical Sciences, Division of Radiology, San Salvatore Hospital, University of L’Aquila, L. Natali Street 1, 67100 L’Aquila, Italy
Giulia Michelini
Department of Biotechnology and Applied Clinical Sciences, Division of Radiology, San Salvatore Hospital, University of L’Aquila, L. Natali Street 1, 67100 L’Aquila, Italy
Giovanni Fuccio Sanzà
Radiodiagnostic and Radiotherapy Unit, University Hospital 'Policlinico Vittorio Emanuele', Santa Sofia Street 78, 95123 Catania, Italy
Alessandra Splendiani
Department of Biotechnology and Applied Clinical Sciences, Division of Radiology, San Salvatore Hospital, University of L’Aquila, L. Natali Street 1, 67100 L’Aquila, Italy
Carlo Masciocchi
Department of Biotechnology and Applied Clinical Sciences, Division of Radiology, San Salvatore Hospital, University of L’Aquila, L. Natali Street 1, 67100 L’Aquila, Italy
*Author to whom correspondence should be addressed.
Abstract
Synovial Sarcoma (SS) is an uncommon neoplasm, very rare in gastrointestinal tract. We report a case of 57 years old man who reported a previous diagnosis of primary left atrial leiomyosarcoma referred for a follow-up CT, that showed findings compatible with ileo-ileal intussusception. The patient underwent surgical resection and pathological analysis showed that the lead point of intussusception were two polypoid lesions referable to SS. The present case report suggests that, although the incidence of SS is rare, it should be considered in the differential diagnosis of any gastrointestinal non-epithelial malignancy.
Keywords: Synovial sarcoma, intussusception, SYT gene, SYT-SSX fusion gene