Stem Cell Therapy for Stroke, Recent Advances, Controversies and Literature Review
Paula Eboli *
Department of Neurological Surgery, Cedars Sinai Medical Center, LA CA, USA
Lindsey Ross
Department of Neurological Surgery, Cedars Sinai Medical Center, LA CA, USA.
Michael Alexander
Department of Neurological Surgery, Cedars Sinai Medical Center, LA CA, USA
*Author to whom correspondence should be addressed.
Abstract
Stem cells based therapy has shown to improve stroke recovery in multiple animal models. Translating these findings into clinical research can result in a potential therapeutic option for stroke. At this moment multiple animal models, different stem cells type and administration route have been used for research purposes. So far ideal timing, type of stem cells and administration routes has not yet been determined. This review summarizes current approaches and progresses in stroke stem cell therapy.
Keywords: Stroke, stem cells, penumbra, neuromodulation, neuro- plasticity