Acute B-Cell Lymphoblastic Leukemia/Acute B-Cell Lymphoblastic Lymphoma Presenting as Bilateral Breast Masses
Burak Ilhan
Department of General Surgery, Istanbul University, Istanbul Medical Faculty, Istanbul, Turkey.
Fatma Sen
Department of Medical Oncology, Institute of Oncology, Istanbul University, Istanbul, Turkey.
Rustu Turkay
Department of Radiology, Istanbul Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Istanbul, Turkey.
Hasan Karanlik *
Surgical Oncology Unit, Institute of Oncology, Istanbul University, Istanbul, Turkey.
*Author to whom correspondence should be addressed.
Abstract
Aims: Metastases of leukemia and lymphoma to both breasts were very rare. We have aimed to report a rare and interesting case that presented with metastases of leukemia and lymphoma to both breasts.
Case Report: A thirty-year-old woman has applied to our department with a four month story of painless masses in both of breasts. We have performed tru-cut biopsies to both breasts after clinical examination. Histological and immuno-histochemical profile analysis have revealed bilateral acute B - cell lymphoblastic lymphoma and acute B - cell lymphoblastic leukemia metastases. A positive response was observed after treating the patient with adjuvant systemic chemotherapy and consolidated radiation therapy. On the sixth month follow-up, no evidence of disease recurrence was identified.
Discussion: In patients presenting with bilateral breast masses, considering that other tumors may metastasize to the breast, the details of this rare case may aid clinicians treating similar patients, and highlight the importance of this situation.
Conclusion: This finding emphasizes the need to accurately identify these tumors as metastases in order to avoid unnecessary procedures and treatments in these patients.
Keywords: Leukemia, lymphoma, breast involvement, metastasis.