IgA Nephropathy may be a Disease Related to Crohn's Disease
Gyong Hoon Kang
Department of Internal Medicine, Kosin University College of Medicine, Busan, Republic of Korea.
Sangeon Gwoo
Department of Internal Medicine, Kosin University College of Medicine, Busan, Republic of Korea.
Soo Young Kim
Department of Internal Medicine, Kosin University College of Medicine, Busan, Republic of Korea.
Joung Wook Yang
Department of Internal Medicine, Kosin University College of Medicine, Busan, Republic of Korea.
Ho Sik Shin
Department of Internal Medicine, Kosin University College of Medicine, Busan, Republic of Korea.
Ye Na Kim *
Department of Internal Medicine, Kosin University College of Medicine, Busan, Republic of Korea.
*Author to whom correspondence should be addressed.
Abstract
IgA nephropathy (IgAN) is the commonest form of glomerulonephritis worldwide and 15–30% of patients will ultimately develop end-stage renal failure. IgAN can be primary (in most cases) or secondary (associated with seronegative arthritis, cirrhosis, coeliac disease, vasculitis, HIV), but is rarely associated with Crohn’s disease (CD). We describe a case of 22 year-old man with CD associated with IgAN. After the patient underwent surgical resection of right colon due to suspected colon tumor, CD was diagnosed. 5 years after right hemicolectomy, microscopic hematuria was developed and a renal biopsy had revealed IgAN (type III). Patients with CD who present with hematuria more commonly have urological complications, but the possibility of renal parenchymal disease should also be considered.
Keywords: IgA nephropathy, Crohn’s disease, hematuria