Journal of Advances in Medicine and Medical Research

Abstract

Aims: To find the antigen specific IgG4 in patients with gastrointestinal complaints and in control group, to demonstrate suitability of detection of IgG4 by using antigen panel.
Place and Duration of Study: Laboratory Management and Consultancy, Riga, Latvia, October 2012 - February 2013.
Methodology: The study included 147 patients (46 men, 101 women, aged from 1 to 76) with different complaints regarding gastrointestinal habitus. Antigen specific IgG4 analysis by using regional adopted antigen panel was executed.
Results: Almost all patients with gastrointestinal complaints -141 out of 147-have at least 2nd level antibodies, while in control group 15 out of 24 have 2nd level of antibodies.
Conclusion: IgG4 antigen specific antibody tests by panels could be used as a screening tool for food intolerance detection.