In vitro Bacteriostatic Effect of a Scaffold with a Mixture of Hypericum perforatum and Azadirachta indica Oil Extracts
Maria Letizia Iabichella *
HELIOS MED ONLUS, International Health Cooperation, Italy.
*Author to whom correspondence should be addressed.
Abstract
Background: Clinical evidences suggest antimicrobial activities of a new oil extract mixture of Hypericum perforatum and Azadirachta indica, included in a polymeric scaffold (or Hyperoil™ Polimeric Substrate - HPS).
Methods: Bacteriostatic activity was investigated on selected strains of Staphylococcus aureus (ATCC® 12598™), Pseudomonas aeruginosa (ATCC® 10145™) and Klebsiella ozaenae AM through standardized in vitro tests.
Results and Conclusion: All bacterial strains were stabilized or reduced in size after 3 and 24 hours contact with the HPS if compared to the empty polymeric scaffolds.
Results showed the bacteriostatic effect of HPS that, added with its anti-inflammatory properties, could explain its tissue repair effects observed in vivo.
Keywords: Hypericum perforatum, Azadirachta indica, Staphylococcus aureus (ATCC® 12598™), Klebsiella ozaenae AM and Pseudomonas aeruginosa (ATCC® 10145™), bacteriostatic effect, scaffold, Hyperoil™ polymeric substrate