Journal of Advances in Medicine and Medical Research

Aim: To determine the presentation and outcome of microbial keratitis among patients at University of Ilorin Teaching Hospital (UITH) in Ilorin, Nigeria.
Methods: A 12-month, prospective, hospital-based longitudinal study was conducted by examining all patients with clinical features of infective keratitis, who met the inclusion criteria. A post-treatment evaluation was done at 6 weeks in all cases, during which visual acuity and any complications were re-assessed. The outcome measures included interval between onset and presentation, extent of corneal involvement and final visual acuity. The data was analysed with the SPSS version 20.0 software.
Results: Fifty-five eyes of 54 patients were studied. There were 32 males (59.3%) and 22 females (40.7%). The mean age was 36.9 years (± 12.1). The predisposing factors were trauma in 30 (55.6%) cases, self-medication with topical steroids in 12 (22.2%) and the use of traditional eye medication in 12 (22.2%). All of the participants presented with pain, tearing, photophobia and reduction in vision. The right eye was involved in 37 patients (67.2%). The presenting visual acuity in the affected eyes was 6/60 or less in 31 (56.4%), 6/60–6/24 in 18 (32.7%) and 6/6–6/18 in 6 eyes (10.9%). At 6-week follow-up, 5 eyes (9.1%) had <6/60 visual acuity, 40 (72.7%) had 6/60–6/24 and 10 (18.2%) had 6/6–6/18.The risk factors for poor outcome were a centrally located lesion (p=0.018), an area of corneal involvement greater than 4mm (p=0.007) and a lesion affecting the deeper layers of the cornea (p=0.002).
Conclusion: Microbial keratitis is a significant cause of ocular morbidity, and public eye-health education is highly desirable as a preventive measure.