Journal of Advances in Medicine and Medical Research 2019-11-14T04:50:54+00:00 Journal of Advances in Medicine and Medical Research Open Journal Systems <p style="text-align: justify;"><strong>Journal of Advances in Medicine and Medical Research (ISSN:&nbsp;2456-8899)</strong> aims to publish research papers, reviews and short communications in the areas of medicine and medical research.&nbsp; JAMMR will not only publish traditional full research reports, including short communications, but also this journal will publish reports/articles on all stages of the research process like study protocols, pilot studies and pre-protocols. JAMMR is novelty attracting, open minded, peer-reviewed medical periodical, designed to serve as a perfectly new platform for both mainstream and new ground shaking works as long as they are technically correct and scientifically motivated.&nbsp;The journal also encourages the submission of useful reports of negative results. This is a quality controlled,&nbsp;OPEN&nbsp;peer reviewed, open access INTERNATIONAL journal.</p> Gordon Dry Gin (Moringa Citrus Blend) Induce Adenomatous Hyperplasia in Female Sprague Dawley Rats 2019-11-14T04:50:54+00:00 E. U. Eric T. O. Alade E. F. Eruvwahwe <p><strong>Objectives:</strong> This study aim to investigate the histopathological effects of binge consumed Gordon’s dry gin moringa citrus blend on the uterus of adult female dawley Sprague rats.</p> <p><strong>Materials: </strong>Fifty female rats (weighing range; 120±2.6 g - 250±3.5 g) were divided into four groups (A, B and C &amp; D). Group A, B, C (15 animals each) were orally administered with Gordon’s dry gin moringa citrus blend, 43% ethanol, and 200 mg/kg moringa extract, respectively, while Group D (5 animals) did not receive any treatment and was used as negative control. In groups A, B, and C, five animals were sacrificed on the 7<sup>th</sup>, 14<sup>th</sup> and 21<sup>st</sup> day of administration, whereas animals of group D were sacrificed on day 21. The uterus of each rat was harvested, processed and stained with haematoxylin and eosin solution for histological analysis.</p> <p><strong>Results:</strong> Results of the study revealed histological alterations in the uterus of treated animals. Such alterations include adenomatous hyperplasia and cystic hyperplasia.</p> <p><strong>Conclusion:</strong> The oral administration of gordon’s dry gin moringa citrus and moringa extract at 200 mg/kg induced cystic and adenomatous hyperplasia in rat uterus, inferring that both gordon dry gin and moringa might yield antifertility activity.</p> 2019-11-12T00:00:00+00:00 ##submission.copyrightStatement##