Main Article Content
Globally, air pollution is the leading environmental cause of human disease and death, and it is a major contributor to cardiovascular disease. Air pollution damages the cardiovascular system by oxidative stress, inflammation, endothelial dysfunction, and pro-thrombotic changes. Ultrafine particulate matter from the combustion of fossil fuels delivers the most potent and harmful elements of air pollution. Coal fly ash is a rich source of nano-sized metal, iron oxide, and carbonaceous particles. Previous findings revealed that coal fly ash is widely utilized in undisclosed tropospheric aerosol geoengineering. Proper iron balance is central to human health and disease, and the harmful effects of iron are normally prevented by tightly controlled processes of systemic and cellular iron homeostasis. Altered iron balance is linked to the traditional risk factors for cardiovascular disease. The iron-heart hypothesis is supported by epidemiological, clinical, and experimental studies. Biogenic magnetite (Fe3O4) serves essential life functions, but iron oxide nanoparticles from anthropogenic sources cause disease. The recent finding of countless combustion-type magnetic nanoparticles in damaged hearts of persons from highly polluted areas is definitive evidence of the connection between the iron oxide fraction of air pollution and cardiovascular disease. Spherical magnetic iron oxide particles found in coal fly ash and certain vehicle emissions match the exogenous iron pollution particles found in the human heart. Iron oxide nanoparticles cross the placenta and may act as seed material for future cardiovascular disease. The pandemic of non-communicable diseases like cardiovascular disease and also rapid global warming can be alleviated by drastically reducing nanoparticulate air pollution. It is crucial to halt tropospheric aerosol geoengineering, and to curb fine particulate emissions from industrial and traffic sources to avoid further gross contamination of the human race by iron oxide-type nanoparticles.
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